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Description
[4] Synthesis Vitamin B-12 cannot be made by plants or animals [5] as only bacteria have the enzymes required for its synthesis

Maoka T, Tanimoto F, Sano M, Tsurukawa K, Tsuno T, Tsujiwaki S, Ishimaru K, Takii K

Declaration of Interest SJ has no conflicts of interest to declare

PMID 4745674
The structure of the complex shows that the enzyme uses several highly conserved residues, e.g., D179, H413, N489, W619, N636, and K638, to form hydrogen bonds and electrostatic interactions with the glucuronic acid moiety of the substrate

Genetics 180 , 857871 (2008)
