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These findings suggest the presence of an FGF21-dependent cardio-hepatic signaling circuit

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Patients with PCOS, which is characterized by a triple pathological network of increased oxidative stress, an unbalanced inflammatory microenvironment, and aberrant vascular remodeling, have dysregulated alterations in uterine molecular markers, which constitute the primary pathological basis for pregnancy failure (Shan et al., 2022)

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