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[24] Note: enzymatic isomerizations and epimerizations play a key role in carbohydrate metabolism, enabling the interconversion of sugars with distinct functional properties

(A) Gross morphology of intact liver from different treatment groups
PPARGC1, Peroxisome proliferator-activated receptor gamma coactivator 1

major targets is presented in Tables 1 and 2, the list of 254 FDA-approved drugs (henceforth referred to as 'Lm254') is presented in Additional file 1: Table S2, and the list of all drugs associated with the 8 synthetic lethal targets is presented in Additional file 1: Table S3

The source of the T-cells in progressive MS lesions is unclear given that the BBB remains largely intact despite the enriched lymphocytic trafficking [72, 73]

Ambra Pozzi (Vanderbilt University, USA), Prof