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A small retrospective study of 15 patients with 42 HR-positive BCBM lesions treated with SRT and CDK4/6 inhibitors reported an mOS of 36.7 months, a 1-year ILC of 88%, and RN in only 2 lesions (5%) (132)

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Taking at least 600 mg NAC anytime acetaminophen is used may help prevent liver toxicity