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Exposure to biological contaminants may promote intestinal dysbiosis, which disrupts the GBAs regular activity and contributes to psychological conditions such as anxiety, stress, depression, and mental disorders as illustrated in Figure 3 (54)

Specifically, knocking down vanin-1 in the liver alleviated insulin resistance and impaired glucose tolerance 39

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This mitochondrial injury promotes the release of apoptotic mediators like cytochrome c and caspases, initiating programmed cell death

The specific structure and cell types allow the lung to recover more easily after the elimination of fibrosis, although pulmonary fibrosis is prone to form large scars compared with hearts with severe diffuse fibrosis