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PLoS Negl Trop Dis2023 Dec 4;17(12):e0011579

Including fermentable fibers in the diet stimulates the production of short-chain fatty acids (SCFAs), which play a role in neuronal signaling and help maintain the balance of the HPA axis [244]

REDEFINE 4: The Tirzepatide Test The results that attracted the greatest market attention came from REDEFINE 4, an 84-week open-label Phase 3 trial reported in February 2026, in which CagriSema was pitted directly against tirzepatide 15 mg, the highest approved dose of Eli Lillys Zepbound

In silico epitope analysis ( Figure 6A ) identified overlapping B- and T-cell epitopes that provide a rationale to explore humoral-cellular immunity mechanisms

doi: 10.1126/science.8052856

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