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Treatment of astrocytes with acetylcarnitine (10100 M for 6 hours) increased the amount and activity of heme oxygenase-1 (HO-1) [131]
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For example, the FAO inhibitor etomoxir reversed cisplatin resistance in cisplatin-resistant cells from OC and GC [57, 64], perhexiline reversed AUY922 resistance in PCa cells [51], and thiolidazine reversed enzalutamide resistance in PCa cells [155]
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It is also incorporated into animal nutrition and pharmaceutical-grade formulations
