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The World Mental Health (WMH) survey, using the WHO Composite International Diagnostic Interview (CIDI 3.0), identified BD as one of the most disabling psychiatric conditions, with affected individuals averaging 41.2 days of role impairment per year 36.5 of which were directly attributed to BD (Nierenberg et al., 2023)

DNA Methyltransferases (DNMTs) DNMTs catalyze the conversion of cytosine to 5-mC at CpG dinucleotides, a critical process for establishing and maintaining DNA methylation patterns

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