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This narrative review provides an overview of the most relevant and recent evidence on the clinical application of NAC, with a focus on respiratory diseases, acetaminophen poisoning, disorders of the central nervous system (chronic neuropathic pain, depression, schizophrenia, bipolar disorder, and addiction), cardiovascular disease, contrast-induced nephropathy, and ophthalmology (retinitis pigmentosa)

The MTHFD1 p.Arg653Gln Variant Alters Enzyme Function and Increases Risk for Congenital Heart Defects. Human Mutation, vol

[PubMed 28371203] 3581

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Moreira, Michael P