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Curr Opin Neurobiol 21: 328338 [DOI] [PMC free article] [PubMed] [Google Scholar] Chen L, Chetkovich DM, Petralia RS, Sweeney NT, Kawasaki Y, Wenthold RJ, Bredt DS, Nicoll RA 2000

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Torres et al., 2006), destabilizing cellular homeostasis and amplifying stress responses (Sharma et al., 2012
In addition to the current clinical interventions available to manage APAP hepatotoxicity, including gastrointestinal track decontamination, NAC administration and liver transplantation, the improvement of mitophagy may stand as a promising novel approach for the management of APAP hepatotoxicity