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Detti says

Can vitamin B12 be used in combination with other therapies for nerve pain

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By selectively inhibiting NNMT, 5-Amino-1MQ preserves SAM and NAD+ precursors, creating a metabolic environment that favors fat oxidation over fat storage

This is problematic because muscle mass contributes to metabolic rate, functional capacity, and long-term health

When both are low, fatigue becomes constant
