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Disrupting mitochondrial Pyruvate uptake directs Glutamine into the TCA cycle away from glutathione synthesis and impairs hepatocellular tumorigenesis

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Therapeutic administration NHPN-1010, an antioxidant compound consisting of HPN-07 and NAC, was prepared in a saline solution that was sterilely-filtered to achieve a final concentration of 60 mg/mL for each component