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In spontaneous mouse models of breast cancer, enhanced SLC6A14 expression promotes the growth of ER-positive breast tumors, while SLC6A14 gene knockout mice exhibit breast tumors with amino acid starvation, weakened mTOR signaling, and reduced cell proliferation (Babu et al., 2015)

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Tainter ML, Cutting WC, Stockton AB (1934) Use of dinitrophenol in nutritional disorders
Understanding the mechanism of SN hyperechogenicity and its relationship with the pathophysiological changes of PD may provide new ideas for the clinical treatment of PD
doi: 10.1038/s41467-019-09455-9

10.1021/acschemneuro.6b00056 34
