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doi: 10.1016/j.biopha.2017.11.016 136 DingLChangMGuoYZhangLXueCYanagitaTet al

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Circulating acylcarnitine profile in human heart failure: a surrogate of fatty acid metabolic dysregulation in mitochondria and beyond

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This gut-mediated conversion highlights a critical practical consideration: when it comes to carnitine supplementation, massive, excessive doses are not necessarily better and can actually be counterproductive