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SOD and CAT can balance the production of oxides and prevent tissue and cells from being damaged by peroxides

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Structure of the cathelicidin motif of protegrin-3 precursor: structural insights into the activation mechanism of an antimicrobial protein

The applicant also referenced a poster presentation by Braun et al

Ten genes (CXCL1, FCAR, CKAP4, SPINK4, CXCL17, OSM, CD4, CXCL9, IL17A, and GZMB) exhibited significant alterations from baseline in responders compared to non-responders at week 8, particularly in terms of endoscopic improvement or histological remission