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Although there are few reports of GPX4 in tumor tissue, GPX4 was found to be increased in colon carcinomas [15] and in hepatocellular carcinomas [16], and decreased GPX4 level has been reported in pancreatic cancer [17], breast cancer cells [18], clear cell renal cell carcinomas [19], and gastric cancer [21]

Jun 15 2009;5(3):205-11

"A controlled comparison of adjuvant lithium carbonate or thyroid hormone in clomipramine-treated patients with obsessive-compulsive disorder"

J Appl Physiol 115(6):909-p19, 2013
Additionally, iron deposition can impair the liver, adipose, and muscle tissues' response to insulin, inducing insulin resistance

R.KongS.-Y.NamB.-H.ChoiI
