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FOXO1 and FOXO3 are essential to numerous endogenous processes as development, differentiation and tumor suppression, roles not prominently attributed to FOXO4(Hosaka et al., 2004

PrP suppression ameliorates the phenotype of Atp7b knockout mice To test the pathological relevance of the PrP-mediated mechanism in vivo, we used Atp7b / mice, a well-characterized WD mouse model

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