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doi: 10.1038/s41598-017-07215-7 83 GertzB.WongM.MartinL

After reaching 8595% confluency, cells were gently washed with PBS (23 times) and starved in 0% FBS DMEM for at least 24 h (unless otherwise specified)

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Although more PD models are needed to validate whether PKM2 is a universal therapeutic target in PD, our results provide preliminary evidence that dimerizing PKM2 is a potential therapeutic approach to protect nigral dopaminergic neurons from oxidative damage

The review also noted GHK-Cus modulation of inflammatory markers, reducing redness and irritation