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However, there is mounting evidence that cellular enzymes referred to as NADPH oxidases are an important source of ROS in humans [2]

DJ-1 functions as a bona fide negative modulator of ferroptosis by sustaining S-adenosyl homocysteine hydrolase activity through altering its interaction with the negative regulator adenosylhomocysteinase like protein 1, thereby maintaining the transsulfuration pathway-mediated biosynthesis of homocysteine and subsequent GSH synthesis (157)

1 2 3 4 5 "Anemia", StatPearls , Treasure Island (FL): StatPearls Publishing, PMID 29763170, retrieved April 1, 2026 "What Is Microcytic Anemia?"

Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1

Shuang et al