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It is generally well-tolerated, with the following side effects [9][18]: GI symptoms (most common): Nausea, vomiting, diarrhea, and abdominal discomfort, particularly at doses above 1,200 mg/day Sulfurous taste/smell: NAC has a distinct sulfur odor and taste that some find unpleasant Headache: Occasionally reported Anaphylactoid reactions (IV use only): Infusion-related reactions including flushing, itching, bronchospasm, and hypotension occur in approximately 10-20% of patients receiving IV NAC for acetaminophen overdose [18] Upper limit: There is no established UL for NAC

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R., Bi, J., Ikegami, S., Masui, K., Gini, B., Yang, H., Gahman, T

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After treatment discontinuation, milk levels decreased to 97 and 68 pmol/L (131 and 92 ng/L), respectively, at 3 months and 106 and 80 pmol/L (144 and 108 ng/L), respectively, at 6 months postpartum

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slightly lower resolution of this dataset, the Na + occupancy, or greater protein flexibility of the substrate-free conformation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Kobayashi M, Itoh K, Suzuki T, Osanai H, Nishikawa K, Katoh Y, Takagi Y, Yamamoto M

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[DOI] [PubMed] [Google Scholar] 54.Zielinska W, Barata H, Chini EN

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