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10.1021/acs.biomac.7b01687 57 GyrgyB.SzabT

Oral capsule protocols The dramatically improved oral bioavailability of the arginate form makes oral administration a viable primary route, not just a convenience compromise

Meanwhile, the toxicity of non-selective TKIs is higher than selective c-Met inhibitors, limiting their prescribed dosage [167]

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In all, these results provide evidence of the remarkable efficacy of 1D228 in suppressing tumor growth without causing any discernible toxicity, surpassing the effectiveness of the current drug Tepotinib

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