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In contrast, cytoplasmic PI(4,5)P 2 puncta in QKO embryos were not associated with PPK-1, suggesting that aberrant accumulation of PI(4,5)P 2 in QKO embryos was not caused by ectopic recruitment of PPK-1 to endosomes (Supplementary Fig

[PubMed: 18322643] 279

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However, intense evidences suggest that lipid peroxidation can be the common feature that initiates and propagates the cell death

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Carnitine deficiency has been reported in chronic illnesses such as cancer [91]