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In OC, it is the sole antioxidant enzyme with high expression that is negatively associated with the overall survival of patients (4-6)

2 CHAC1 as a central integrator of glutathione homeostasis, stress signaling and ferroptosis Glutathione homeostasis is essential for cellular and organismal health due to its central role in maintaining redox balance

Addressing social and environmental factors is crucial for mitigating stress-related liver disorders and improving overall health outcomes 2,3

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D-limonene exhibits anti-inflammatory and antioxidant properties in an ulcerative colitis rat model via regulation of iNOS, COX-2, PGE2 and ERK signaling pathways

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