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doi: 10.1155/2017/9351507 [DOI] [PMC free article] [PubMed] [Google Scholar] 200

doi: 10.1083/jcb.201611194
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EMS, especially OEM, can lead to follicular inflammation and oxidative stress
In particular, the expression of the insulin receptor protein, which regulates energy metabolism, has been positively correlated with mammalian longevity (Ma S
As a result, defenses against ROS are activated 14 by an array of nonenzymatic antioxidants [metabolites such as ascorbate (AsA), carotenoids, glutathione (GSH) and proline] and antioxidant enzymes [such as guaiacol peroxidases (GPOX), catalase (CAT), superoxide dismutase (SOD) and AsA-GSH cycle enzymes like glutathione reductase (GR) ascorbate peroxidase (APX), monodehydroascorbate reductase (MDHAR), dehydroascorbate reductase (DHAR)], work together for detoxification of ROS 7,8,15,16,17,18,19,20
