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nsSNP have the potential to alter the function of their protein, either directly or via disruption of structure 15

Under oxidative stress conditions, the capacity of PEX5 to transport CAT is significantly reduced, resulting in an accumulation of CAT within the cytoplasm, thereby providing a protective effect against H 2 O 2 -induced oxidative damage in the cytoplasm [156]

Metab 2000, 278, E967E976

Bioavailability assays ensure optimum cellular uptake

This was attributed to the antioxidant activity of flavonoids and the increased activity of superoxide dismutase and peroxidase in these plants [241]