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The phospholipid transfer protein in plasma transfers amphiphilic lipids between circulating lipoproteins and between lipoproteins, cells and tissues, and it may assist in the neutralization and clearance of bacterial lipopolysaccharides or endotoxins

Larger trials are needed to confirm these preliminary findings and further evaluate the usefulness of supplemental lipoic acid in the prevention and/or management of neurodegenerative diseases

The authors proposed that these chromatin modifications facilitated the rapid up-regulation of effector genes and regulated the memory functions of T cells [96]

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In this context, as well as elsewhere, NHR-49 regulates the expression of genes involved in lipid metabolism and mitochondrial function, suggesting a mechanism for its protective effects against A1-42 toxicity (Leiteritz et al., 2020)