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Supplementation of Ctt, NaSH, or taurine also significantly alleviated the resistance of HepG2 to the sorafenib treatment in response to HNF4 knockdown (Fig
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Emerging research suggests that disturbances in BA metabolism not only exacerbate metabolic imbalance but also promote ferroptosis via lipid peroxidation
Interestingly, we were not able to detect S6K in its phosphorylated form in U87Mut clone, which would suggest a lower activity of mTORc1 in this cell line and hence a lower protein translation rate
The authors also thank Traci Raley, MS, ELS, from Liwen Bianji (Edanz) (www.liwenbianji.cn) for editing a draft of this manuscript
Calcitriol and its analogs establish the immunosuppressive microenvironment that drives metastasis in 4T1 mouse mammary gland cancer
