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Among the ATF4-driven outputs is the transcription factor CHOP (C/EBP-homologous protein), whose abundance rises markedly in response to PERK-eIF2 signaling and promotes pro-death programs when ERS is unresolved (110)

The supernatant was discarded, and the pellet was washed twice (5mL of 0.9% NaCl)
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Although somatic mutation is hallmark of tumorigenesis, not all tumors produce sufficient immunogenic antigens to induce a robust endogenous immune response

Supplementary Figure 2A-B) while the precursor of non-methyl C-atoms of methionine, aspartate, was never 13 C-enriched above 18% and hardly 13 C-enriched when photorespiration was suppressed under N 2 (0% O 2 ) as a background gas (Fig

Deadly conversations: nuclear-mitochondrial cross-talk
