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Experimental approaches to delineate key components and their biological roles In mammals, the cholesterol synthesis sub-branch of the mevalonate pathway has been the most intensely studied due to the proposed involvement of cholesterol in atherosclerosis
Total protein extracts were prepared by standard procedures and analyzed by PAGE using the following antibodies: caspase 3 active form, iNOS (Santa Cruz Biotechnology, Santa Cruz, CA, USA) and Ub (Sigma-Aldrich)
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Crystal structure of human lysosomal acid lipase and its implications in cholesteryl ester storage disease
