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High doses are generally considered safe, though some people may experience minor side effects

A B12 deficiency can lead to anemia, which reduces the oxygen-carrying capacity of the blood, resulting in fatigue, weakness, and shortness of breath

Methylation happens when nutrients such as Folic Acid, Vitamin B6 and Vitamin B12 donate a methyl group (a molecule combo of one carbon and three hydrogen), and transfer it to a protein, enzyme, hormone or right onto DNA

The final step in this pathway is the conversion of phosphocholine into phosphatidylcholine, a process catalyzed by the enzyme 1,2-diacylglycerol cholinephosphotransferase

In preclinical trials, both of the peptides were observed to have affected the patterns associated with fat cells in research subjects

Department of Health and Human Services, ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional/