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Mushroom fermentation typically increases protein digestibility which is dependent on the protein material solubility, presence of anti-nutrients including phytic acid and protease inhibitors (Afify, El-Sawah, Ali, El-Rahman, & Biotechnology, 2012)
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Flavones are characterized by the presence of a double bond between carbon 2 and 3, a keto group in carbon 4 and a B ring linked to carbon 2

Reuteri RC-14 Helps Resolve Moderate Diarrhea and Increases CD4 Count in HIV/AIDS Patients." J Clin Gastroenterol 42.3 (2008): 239-43

Similarly, studies utilizing kidney tubule-specific autophagy-deficient mouse models have provided more conclusive evidence regarding this process
