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Furthermore, both GSQs (124) and QQ-protein thiols have been shown to be unstable and transient -lasting for minutes and hours instead of days- suggesting an overestimation of the proposed in vitro toxicity (125)

T cell protein tyrosine phosphatase prevents STAT1 induction of claudin-2 expression in intestinal epithelial cells

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VRK2 overexpression induced an increase in the expression of SLC7A11 at the PM level but not at the whole cell level

On one hand, this activates the Nrf2 pathway, increasing the transcription of antioxidant enzymes 46,47