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Description
General pathways of pain sensation and the major neurotransmitters involved in pain regulation

Cytokine Growth Factor Rev

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These data indicate that the lack of agreement in findings on melatonin levels in depressed individuals may be a result of (1) the diversity of behavioral and etiological phenomena in depressive states [as previously commented ( Though the immediate mechanisms of action of current antidepressants are well-understood, the delay in clinical outcome conveys the gap of knowledge on the complete pathways that ultimately determine the clinical response

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