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On the other hand, overactivation of this pathway can lead to intestinal damage and the development of inflammation

demonstrated that reducing STAT3 expression revealed luteolins ability to inhibit phosphorylation within the JAK/STAT signaling cascade while concurrently increasing SOCS3 expression

Oct 2008;84(4):988-993
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Reductive carboxylation supports redox homeostasis during anchorage-independent growth
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