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Women have higher quantities of estrogen, but small amounts of testosterone for libido, muscle mass, mood, etc
It is natural to speculate whether the inhibition of GS and GCL is an important evolutionary mechanism to keep GSH high, but not too high, in females during the childbearing years

Sulfur provides the chemical "glue" that allows glutathione to trap toxins and neutralize free radicals

In contrast, bacterial lipopolysaccaride (LPS) is able to trigger thyroiditis in NOD H2h4 mice, by interacting with TLR4 expressed on thyrocytes

doi: 10.3390/cells8020158 82 ChaveyCMariBMonthouelMNBonnafousSAnglardPVan ObberghenEet al