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BPC-157 would address one of those targets

Goldman 2016)

This barrier prevents the interaction of luminal microorganism with the surface of the epithelium

von Boyen G.B.T
Folic acid is not a substitute for vitamin B12 although it may improve vitamin B12 deficient megaloblastic anemia

Chiocchetti R, Mazzuoli G, Albanese V, Mazzoni M, Clavenzani P, Lalatta-Costerbosa G, Lucchi ML, Di Guardo G, Marruchella G, Furness JB (2008) Anatomical evidence for ileal Peyers patches innervation by enteric nervous system: a potential route for prion neuroinvasion
