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In the first step, trimethylamine (TMA) is generated from the dietary nutrients (e.g., choline, phosphatidylcholine, L-carnitine) by the activity of gut microbiota TMA lyases

6 Tumor-suppressive properties of L-carnitine Overall, preclinical evidence suggests that L-carnitine may contribute to hepatoprotection, although robust clinical evidence for anti-tumor efficacy in humans is currently lacking

also reported similar research conclusions

As a potential link between red meat consumption and the increasing risk of cardiovascular disease, trimethylamine-N-oxide (TMAO) has been indicated [8]

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Sin embargo, en la prctica clnica habitual nos encontramos con RNMBP que necesitan NP de manera prolongada, durante ms de un mes