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Interestingly, the turning point in the GSH level timecourse of females (age 45) is within the period of menopause

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Studies have shown that it can reduce the release of pro-inflammatory factors by inhibiting the NF-B and COX-2 pathways, and activate Nrf2 to enhance the activity of antioxidant enzymes (45)

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382 IL-1 sustains Fe-S cluster maintenance to repress iron accumulation and ferroptosis

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In fact, when we studied cold response in BAT and iWAT in untreated mice, we also found that Ckb is upregulated (Extended Data Fig

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Harris BD, Moody EJ, Gu ZQ, Skolnick P (1995b)

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10.4081/hls.2024.12563 3 AnsariniyaH.ZareF.MosaffaN.IdaliF.ShabaniM.HadinedoushanH

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