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The extracts were filtered to obtain the final solution for downstream analysis 47,48

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Additionally, by phosphorylating p62, mTORC1 facilitates the binding of p62 and Keap1, which causes Keap1 to degrade and NRF2 to accumulate (107)

10.1067/mai.2002.124467 111 PulleritsT.PraksL.SkooghB.-E.AniR.LtvallJ

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In a follow-up study, only one patient out of 62 treated with NAC within 10 hours developed severe liver injury as compared to a retrospective control group, which showed that 33 out of 57 patients (58%) developed severe liver injury after an acetaminophen overdose [14]