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Moreover, many tumors including PCa cells shed DNA into the serum or other easily accessible body fluids (e.g., semen, urine), simplifying the detection of GSTP1 epimutations in early tumorigenesis stages

subsequently, glutamate will convert to -ketoglutarate (-KG) as the main component of Tricarboxylic Acid cycle (TCA) by mitochondrial glutamate dehydrogenases (GLUD), -KG mainly incorporates into TCA cycles to assist the production of NADPH and nucleotide synthesis

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Our results, obtained in the mdx mouse model, also indicate a higher number of Pax7 + SCs in dystrophin-deficient mice, suggesting a lack of association between defects in the regenerative potential of SCs and their number [34,35,36]

The histone deacetylase complex MiDAC regulates a neurodevelopmental gene expression program to control neurite outgrowth
