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Glutamine: Supports the mucosal barrier of the gut Reduces intestinal permeability ("leaky gut") Fuels immune activity within the gut-associated lymphoid tissue (GALT) This makes it a valuable therapeutic nutrient for people with gastrointestinal disorders such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), Crohns disease, and ulcerative colitis

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doi: 10.3389/fmicb.2022.979719

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Active MTORC1 inhibits autophagy by binding and phosphorylating the ULK complex composed of ULK1, ULK2 (unc-51 like autophagy activating kinase 2), and ATG13 (autophagy related 13) proteins [170]

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For this reason, some healthcare providers use NAC alongside other medications to help treat some diseases and conditions related to oxidative stress and inflammation, including polycystic ovary syndrome (PCOS), ulcerative colitis, and neurodegenerative diseases like Alzheimers and Parkinsons

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