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However, clinical studies have reported a higher all-cause mortality among patients treated with cefiderocol for hospital-acquired pneumonia, and thus treatment regimens require close monitoring to avoid toxic side-effects, particularly among elderly patients ( in vivo and siderophore-mediated iron acquisition is a minor contributor to total iron acquisition in NTHi (Morton et al., 2010b)
Malkin, 2008)

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Practices see $100K$900K in additional annual revenue