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Potential Benefits Appetite regulation: Stronger, longer-lasting satiety that helps reduce calorie intake [7] [8]

Importantly, our technique is based on two different tags flanking the two ends of the protein, which is an efficient tool to remove degraded proteins and, therefore, enriches full-length proteins

10.1016/j.euroneuro.2018.05.009 44 FarajP.HaslemoT.TranJ

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For deeper metabolomic coverage, samples were again dried and resuspended in 50% ACN (v/v) and analyzed using two orthogonal chromatographies (Waters BEH Amide and T3, described below) on an Orbitrap ID-X in ESI positive mode

In this study, nefazodone was chosen as a model compound to examine the effectiveness of the current approach (Figure 1)