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Vitamin B12 (cobalamin) is essential for maintaining the protective myelin sheath around nerves, and deficiency can cause peripheral neuropathy, gait disturbances, memory problems, and in severe cases, subacute combined degeneration of the spinal cord

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Although the mechanism is not known, the Grx3/4Fra2 complex may acquire a [2Fe-2S] cluster in iron-replete cells, and this complex may cause Aft1 to multimerize and exit the nucleus

Crypt stem cells as the cells-of-origin of intestinal cancer