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Bemarituzumab targeting FGFR2b achieved a 53% ORR in gastric cancer harbouring FGFR2 overexpression or amplification [428]
However, the absence of IF disrupts the absorption of both free and food-bound cobalamin, as well as the daily reabsorption of approximately half of the 1.4 g of biliary cobalamin
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[DOI] [PMC free article] [PubMed] [Google Scholar] 111.Baxter R.C., Martin J.L
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YbdK is a carboxylate-amine ligase with a gamma-glutamyl:Cysteine ligase activity: crystal structure and enzymatic assays
