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2.1.1 Passive targeting During passive targeting, biomaterials-based nanocarriers generally act via physical and chemical interactions (hydrophobic and electrostatic interactions) as well as physical factors (such as carrier size and mass) to achieve targeted drug delivery ( Inflammatory responses can increase the permeability of blood vessels, subsequently triggering the extravasation through leaky vasculature and inflammatory cell-mediated sequestration (ELVIS) ( in vivo biodistribution study of the nanoliposomes was not performed

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Liu, Y., Li, P., Fan, L

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