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This study was performed on a larger group of 200 people where a straight infusion of 2030 mL D-limonene (97% solution) effectively eliminated gallstones of the size range between 0.5 and 1.5 cm with an average diameter of 1.0 cm in 141 individuals

doi: 10.1101/cshperspect.a008862 4 WalusinskiO

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For the most part, however, their physiological role in man is not well characterized