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Side effects of endocrine therapy are particularly predominant amongst premenopausal patients taking GNRH agonists for ovarian suppression [26]

10.1021/acsnano.4c15283 [DOI] [PMC free article] [PubMed] [Google Scholar] 121.Pichla M, Bartosz G, Sadowska-Bartosz I

Further research suggested that it may influence enkephalin levels only by inhibiting their degradation, and it does not appear to bind or directly affect opioid receptors in the brain