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Our skin repairs itself, but this ability weakens over time

Medications: acid-reflux drugs (PPIs) and some diabetes medications (such as metformin) can interfere with B12 absorption

ACS Infect Dis 7:174188 Campos-Pardos E, Uranga S, Pic A, Gmez AB, Gonzalo-Asensio J (2024) Dependency on host vitamin B12 has shaped Mycobacterium tuberculosis complex evolution

The body excretes any excess through urine, so there are minimal side effects, even at high doses

Figure 4 One limitation of examining these clinical trial data in this way is that the ASD population that received the placebo, although similar in development, age and gender, for various reasons, had some differences baseline metabolic characteristics which could affect the effectiveness of the treatment being studied