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Without sufficient antioxidant defenses, toxins and oxidative stress can accumulate

FIGURE 2 The second category regroups prodrugs non-structurally related to GSH

Next, we will discuss each of these strategies in detail, exploring their specific effects, mechanisms, and potential clinical applications

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The researcher is not choosing a format based on conveniencethey are selecting the route that maximizes the probability of the compound reaching its intended site of action at a sufficient concentration

In in vivo studies, lutein markedly and dose-dependently enhanced its inhibition of 7-ethoxyresorufin- O -deethylase (EROD), 7-pentoxy-resorufin- O -depentylase (PROD), and 7-methoxyresorufin- O -methylase (MROD) activity